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September 5, 2025Egyptian Journal of Dermatology and VenerologyOpen Access

Gemcitabine induced vasculitis: an increasing trend

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Authors

PDPankaj DasIndian Agricultural Statistics Research InstituteVGVinay GeraArmed Forces Medical CollegeABAnuj BhatnagarArmed Forces Medical College

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Implication

Case report reveals cutaneous vasculitis after gemcitabine treatment in lung cancer, suggesting heightened awareness of vascular adverse effects.

Key Points

  • Gemcitabine therapy may lead to cutaneous vasculitis, highlighting a concerning trend in vascular adverse events.
  • The Naranjo score indicated a probable link between gemcitabine and vasculitis after a patient presented with purpura.
  • Diagnosis involved histopathological examination showing neutrophilic infiltration and perivascular activity around the dermal vessels.
  • With discontinuation of gemcitabine and treatment with corticosteroids, the patient's symptoms resolved, suggesting a need for careful monitoring.

Cite This Study

Das et al. (2025) studied this question.

synapsesocial.com/papers/68bb49db6d6d5674bcd003aehttps://doi.org/10.4103/ejdv.ejdv_82_24
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Also Consider

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  1. 1Gemcitabine-induced peripheral vascular disease and prolonged response in a patient with metastatic pancreatic adenocarcinoma: A case report2023 · 1 citations
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  3. 3Gemcitabine-associated digital necrosis in metastatic breast cancer2023 · 5 citations
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  5. 5Risk of venous and arterial thromboembolic events in cancer patients treated with gemcitabine: a systematic review and meta‐analysis2013 · 25 citations