Background: Diabetes Mellitus (DM) is a common metabolic disorder resulting from insufficient insulin secretion or insulin action that leads to elevated blood glucose levels. The metabolic disorders associated with DM cause secondary pathophysiological changes in multiple organ systems leading to acute and chronic complications. Insulin resistance is frequently higher in patients with diabetes or microalbuminuria in the context of renal disease, which may accelerate the progression of Diabetic Kidney Disease. Methods: A cross-sectional study conducted at the Galiawa Teaching Center in Erbil, Iraq. The study included 100 patients who had been diagnosed with type 2 diabetes mellitus. lipid profile, glycated hemoglobin (HbA1C) and albumin creatinine ratio (ACR) were done for them, then statistically analyzed. Results: 100 participants were included, the mean age was 57±9 years, ranging from 34 to 80 years. About 60% of the participants were females and 40% were males. The most frequent category was stage A2, observed in 37 patients (37%). Additionally, 86% of participants had an eGFR within stages 1 to 3a. low-density lipoprotein (LDL) levels showed a statistically significant difference between ACR groups A1, A2 and A3 (p-value = 0.000), with the highest mean observed in group A3 (136±26 mg/dL). Conclusion: There is a significant correlation between mean LDL and UACR. And insignificant association between mean TC, mean TG and mean HDL with UACR.
Hameed et al. (Tue,) studied this question.
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