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September 5, 2025The Kaohsiung Journal of Medical SciencesOpen Access

Impact of Depth of Invasion in Node‐Negative Oral Tongue Cancer Treated With Surgery Alone

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Authors

PHPo‐Wen HsiaoChang Gung University YLYu‐Tsai LinNational Sun Yat-sen University HCHui‐Ching ChuangNational Sun Yat-sen University

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Implication

Retrospective analysis reveals that depth of invasion predicts local recurrence and mortality in node-negative oral tongue cancer patients, highlighting its clinical importance.

Key Points

Each millimeter increase in depth of invasion significantly raises the risk of all-cause mortality and local recurrence.
Patients with a higher depth of invasion had a hazard ratio of 1.07 for all-cause mortality, indicating increased risk.
Analysis of 243 node-negative oral tongue cancer patients treated with radical surgery shows depth of invasion as a key predictor.
These findings suggest that depth of invasion can guide clinical decision-making for post-surgery treatment approaches.

Cite This Study

Hsiao et al. (2025) studied this question.

synapsesocial.com/papers/68bb49db6d6d5674bcd0045b https://doi.org/10.1002/kjm2.70102

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Implication

Retrospective analysis reveals that depth of invasion predicts local recurrence and mortality in node-negative oral tongue cancer patients, highlighting its clinical importance.

Impact of Depth of Invasion in Node‐Negative Oral Tongue Cancer Treated With Surgery Alone

Discussion

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Implication

Key Points

Cite This Study

Impact of Depth of Invasion in Node‐Negative Oral Tongue Cancer Treated With Surgery Alone

Discussion

Member takes

Implication

Key Points

Cite This Study

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