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Adenomatoid hyperplasia of minor salivary glands: report of three cases with immunohistochemical findings and literature review

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Case reports reveal histopathological insights, immunohistochemical findings, and clinical implications of adenomatoid hyperplasia.

Adenomatoid hyperplasia lesions showed enlarged lobules of mucous acini, and fibrous stroma, indicating unique characteristics.
Immunohistochemical analysis revealed positive markers like CAM 5.2 and CK7 in acinar cells, essential for diagnosis.
The Ki67 labeling index was between 1% and 5%, suggesting low proliferative activity within the lesions.
Recognizing adenomatoid hyperplasia is vital to prevent misdiagnosis as benign or malignant salivary gland tumors.

Carmelo Urso (2025) studied this question.

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