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September 5, 2025AntioxidantsOpen Access

Clinical Evaluation of Oxidative Stress Markers in Patients with Long COVID During the Omicron Phase in Japan

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Clinical evaluation reveals oxidative stress markers differ by gender in long COVID patients, suggesting potential predictive value.

Oxidative stress markers were significantly higher among females with long COVID compared to males.
Median serum d-ROM levels were 533.8, while OSI was 2.0, indicating notable oxidative stress in the population.
Significant associations were found between oxidative stress markers and inflammatory markers like C-reactive protein.
Higher OSI levels were observed in patients with brain fog, suggesting a potential link to psycho-neurological symptoms.

Mese et al. (2025) studied this question.

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