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This is a Observational study (also classified as: Animal Study).

Synthesis, Characterization, and Molecular Docking Analysis of Triazole, Schiff Bases, and Tetrazole Derivatives Derived from Nitrilotriacetic Acid against Breast Cancer Targets

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This research demonstrates the synthesis of triazole and tetrazole derivatives, suggesting strong binding to breast cancer targets PI3K and HER2.

The novel compounds showed binding affinities up to -9.8 kcal/mol, suggesting significant anticancer potential.
Characterization methods included FT-IR, ¹H-NMR, and ¹³C-NMR for the synthesized derivatives.
The synthesis followed a three-step process, starting from nitrilotriacetic acid to produce various heterocyclic compounds.
Molecular docking analysis revealed strong interactions with key breast cancer targets, indicating further therapeutic potential.

Khalaf et al. (2025) studied this question.

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This research demonstrates the synthesis of triazole and tetrazole derivatives, suggesting strong binding to breast cancer targets PI3K and HER2.