Figure S1 from The African-Specific Variant in the Duffy Antigen Receptor for Chemokines Gene, CD8⁺ T-Cell Density, and Aggressive Breast Cancer Subtypes in Black Women

Nisha M. Nair; Lucas Mendicino; Peter N. Fiorica; Angela R. Omilian; Thaer Khoury; Wiam Bshara; Elisa V. Bandera; Chi‐Chen Hong; Yara Abdou; Jo L. Freudenheim; Anselm Hennis; Katie M. O’Brien; Gary Zirpoli; Eboneé N. Butler; John Obafunwa; Clarice R. Weinberg; Dezheng Huo; Bingshan Li; Xingyi Guo; Julie R. Palmer; Christopher A. Haiman; Wei Zheng; Song Yao; Christine B. Ambrosone

doi:10.1158/1055-9965.30028976

Key Points

Higher CD8+ T-cell density is associated with certain ACKR1/DARC genotypes in black women.
The study included 428 participants, revealing a significant distribution of T-cell density linked to genetic factors.
Methodology involves box plot analysis of CD8+ T-cell density in relation to ACKR1/DARC genotype status.
Findings highlight the potential impact of genetic variation on breast cancer subtype severity in the examined population.

Implication

Analysis shows variations in CD8+ T-cell density by ACKR1/DARC genotype in black women, suggesting implications for breast cancer subtype aggressiveness.

Abstract

Supplemental Figure S1. Log-transformed CD8+ T-cell density per mm2 by ACKR1/DARC genotype. Figure displays box plot distribution of CD8+ T-cell density per mm2 according to ACKR1/DARC genotype (N=428).

Discussion

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Cite This Study

Nair et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd0286b https://doi.org/10.1158/1055-9965.30028976

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Figure S1 from The African-Specific Variant in the Duffy Antigen Receptor for Chemokines Gene, CD8⁺ T-Cell Density, and Aggressive Breast Cancer Subtypes in Black Women

Key Points

Implication

Abstract

Discussion

Cite This Study

Figure S1 from The African-Specific Variant in the Duffy Antigen Receptor for Chemokines Gene, CD8⁺ T-Cell Density, and Aggressive Breast Cancer Subtypes in Black Women

Key Points

Implication

Abstract

Discussion

Cite This Study

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