Figure S2 from The African-Specific Variant in the Duffy Antigen Receptor for Chemokines Gene, CD8⁺ T-Cell Density, and Aggressive Breast Cancer Subtypes in Black Women

Nisha M. Nair; Lucas Mendicino; Peter N. Fiorica; Angela R. Omilian; Thaer Khoury; Wiam Bshara; Elisa V. Bandera; Chi‐Chen Hong; Yara Abdou; Jo L. Freudenheim; Anselm Hennis; Katie M. O’Brien; Gary Zirpoli; Eboneé N. Butler; John Obafunwa; Clarice R. Weinberg; Dezheng Huo; Bingshan Li; Xingyi Guo; Julie R. Palmer; Christopher A. Haiman; Wei Zheng; Song Yao; Christine B. Ambrosone

doi:10.1158/1055-9965.30028973

Key Points

Non-significant odds ratios for breast cancer overall were found concerning the rs2814778 variant.
The analysis includes estimates for ER- and TNBC showing no statistically significant results.
Meta-analysis evaluated multiple studies to ensure comprehensive data on breast cancer risk factors.
Insights may guide future research on aggressive breast cancer subtypes in black women.

Implication

Meta-analysis shows non-significant odds ratios for breast cancer, ER-, and TNBC linked to the rs2814778 variant.

Abstract

Supplemental Figure S2. Meta-analysis full forest plots from AABCG for rs2814778 in relation to risk of breast cancer overall, ER- and TNBC. Figure shows non-significant odds ratio (OR) estimates for breast cancer risk overall, ER- and TNBC for ACKR1/DARC variant, rs2814778 in reference to controls.

Discussion

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Cite This Study

Nair et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd028e1 https://doi.org/10.1158/1055-9965.30028973

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Figure S2 from The African-Specific Variant in the Duffy Antigen Receptor for Chemokines Gene, CD8⁺ T-Cell Density, and Aggressive Breast Cancer Subtypes in Black Women

Key Points

Implication

Abstract

Discussion

Cite This Study

Figure S2 from The African-Specific Variant in the Duffy Antigen Receptor for Chemokines Gene, CD8⁺ T-Cell Density, and Aggressive Breast Cancer Subtypes in Black Women

Key Points

Implication

Abstract

Discussion

Cite This Study

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