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September 5, 2025MedicineOpen Access

A Mendelian randomization study of the associations between depression, anxiety and clinical conditions including thyroid nodules, flatulence, and irregular menstruation

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Authors

ZBZheng BiLWLujie WangJLJinju Li

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Overview

Mendelian randomization reveals depression worsens thyroid nodules and irregular menstruation, suggesting vital mental health implications.

Key Points

  • Depression significantly increases the risk of developing thyroid nodules and menstrual irregularities.
  • The odds ratio for thyroid nodules linked to depression was 1.75 and for irregular menstruation was 1.005.
  • Mendelian randomization using genetic data assessed various clinical conditions to explore causality.
  • Findings emphasize the need to address mental health in the management of physical health issues.

Cite This Study

Bi et al. (2025) studied this question.

synapsesocial.com/papers/68bb5f7a6d6d5674bcd03cd0https://doi.org/10.1097/md.0000000000044041
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