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October 17, 2025Actas Españolas de PsiquiatríaOpen Access

Mendelian Randomisation Analysis of Dietary Exposures and Potential Risks of Anxiety and Depression

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Authors

XYXiaoling YuQingdao UniversityRHRunxia HangNanjing General Hospital of Nanjing Military CommandQGQian GanChinese Center For Disease Control and Prevention

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Overview

Two-sample Mendelian randomisation analysis reveals dietary exposures affect anxiety and depression risks, suggesting potential intervention strategies.

Key Points

  • High beef and cereal consumption reduces depression risk, while tea is linked to an increased risk.
  • Specific dietary exposures were assessed using causal estimates from genome-wide association studies.
  • Non-oily fish intake increases anxiety risk, whereas unsalted peanuts show a protective effect.
  • Findings indicate targeted dietary interventions may help prevent or manage anxiety and depression.

Cite This Study

Yu et al. (2025) studied this question.

synapsesocial.com/papers/68f199ccde32064e504dd1d5https://doi.org/10.62641/aep.v53i5.1969
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Also Consider

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  1. 1Genetic predispositions for anxiety disorders and major depressive disorder affect current dietary habits in older patients with lifestyle-related diseases2026
  2. 2Associations between dietary habits and depressive disorder: A diet-wide Mendelian randomization study2026 · 1 citations
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  4. 4Improving precision management of anxiety disorders: a Mendelian randomization study targeting specific gut microbiota and associated metabolites2024 · 6 citations
  5. 5A Mendelian randomization study of the associations between depression, anxiety and clinical conditions including thyroid nodules, flatulence, and irregular menstruation2025