Figure S5 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Key Points

• EMT induction occurs following treatment with etomoxir and MCM, enhancing the metastatic potential.
• Bulk transcriptomics highlights the role of metabolic changes in promoting tumor metastasis in pancreatic cancer.
• Research showcases PPARδ's orchestrating effects on promoting a metabolic response linked to cancer progression.
• Findings may guide therapeutic strategies targeting metabolic pathways in pancreatic cancer management.