Figure S12 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Key Points

• Downregulation of MYC reverses the prometastatic phenotype, enhancing treatment potential.
• Experiments show that blocking PPARδ can alter metabolic responses in pancreatic cancer cells.
• Analysis focuses on the influence of microenvironmental cues in cancer cell metabolism.
• Findings may help identify new strategies for targeting pancreatic cancer metastasis.