Figure S1 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Key Points

• Increased expression of prometastatic genes occurs in pancreatic cancer cells due to environmental stressors.
• Key factors include energy deprivation and stromal cell interactions that enhance tumor aggressiveness.
• The approach utilized co-culture methods to assess the impact of microenvironment on pancreatic cancer cells.
• These findings highlight pparδ as a potential therapeutic target in pancreatic cancer, warranting further investigation.