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September 10, 2025
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Table S1 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer
BP
Beatriz Parejo-Alonso
Instituto de Investigación Sanitaria Aragón
DB
David Barneda
Babraham Institute
ST
Sara Maria David Trabulo
AstraZeneca (United Kingdom)
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Key Points
The study uncovers PPARδ's role in promoting metabolic changes linked to pancreatic cancer progression.
Primary pancreatic cancer (PDAC) cells exhibited a notable metabolic response driven by microenvironmental cues.
The analysis focuses on PPARδ as a crucial factor in the tumor microenvironment affecting cancer cell behavior.
These findings highlight the potential of targeting PPARδ for therapeutic approaches in pancreatic cancer.
Abstract
Primary PDAC cells used in this study
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Parejo-Alonso et al. (Tue,) studied this question.
synapsesocial.com/papers/68c182609b7b07f3a060f59b
https://doi.org/https://doi.org/10.1158/0008-5472.30029429
Table S1 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer | Synapse