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September 2, 2025Open Access

Table S6 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Beatriz Parejo-Alonso David Barneda Sara Maria David Trabulo Sarah Courtois Sara Compte-Sancerni Jelena Zurkovic Laura Ruíz-Cañas Quan Zheng Jiajia Tang Matthias M. Gaida Ulf Schmitz Pilar Irún Laure Penin-Peyta Shanthini Mary Crusz Petra Jagušt Pilar Espiau-Romera Alba Royo-García Andrés Gordo-Ortiz Mariia Yuneva Meng‐Lay Lin Shenghui Huang Ming-Hsin Yang Ángel Lanas Bruno Sáinz Christoph Thiele Christopher Heeschen Patricia Sancho

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Key Points

Targeting PPAR-δ significantly modulates metastasis in pancreatic cancer.
Pharmacological intervention leads to notable changes in metabolic response.
The study focuses on how microenvironmental cues drive the prometastatic activities.
Results indicate potential pathways for developing new therapeutic strategies.

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Implication

Pharmacological targeting of PPAR-δ influences metastasis and metabolic response in pancreatic cancer, suggesting new treatment avenues.

Abstract

Pharmacological targeting of PPAR-δ modulates metastasis in vivo

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Cite This Study

Parejo-Alonso et al. (2025) studied this question.

synapsesocial.com/papers/68c182609b7b07f3a060f5ad https://doi.org/10.1158/0008-5472.30029414

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Table 1 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer2025
2Figure S14 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer2025
3Table S1 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer2025
4Figure S8 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer2025
5Table S3 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer2025

Table S5 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer2025
Table S2 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer2025
Table S4 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer2025