Figure S13 from PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Key Points

• MYC inhibition influences EMT gene expression, impacting metabolic responses in pancreatic cancer.
• Key evidence shows that alterations induced by PGC1A overexpression affect functionality in cancer contexts.
• Analysis focusing on microenvironmental cues and their role in pancreatic cancer highlights metabolic dependencies.
• Understanding these mechanisms may enable better strategies to target pancreatic cancer progression.