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This is a Literature Review study.

September 10, 2025CureusOpen Access

Acute Salicylate Toxicity: A Narrative Review for Emergency Clinicians

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This narrative review highlights management of salicylate toxicity and its clinical implications in emergencies.

Acute salicylate toxicity can lead to significant morbidity and mortality, often requiring prompt intervention.
Symptoms of salicylate toxicity include respiratory alkalosis, metabolic acidosis, and altered mental status.
Immediate treatment strategies involve gastrointestinal decontamination and fluid resuscitation to stabilize patients.
Severe cases may necessitate hemodialysis, particularly when patients exhibit high salicylate levels or significant acid-base disorders.

Sidlak et al. (2025) studied this question.

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