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September 10, 2025Frontiers in Medicine0 citationsOpen Access

Elevated SIRI Linked to Atrial Fibrillation Risk in COPD Patients

Association between systemic inflammation response index and atrial fibrillation in chronic obstructive pulmonary disease: a multicenter cross-sectional study

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Authors

HXHao XuTLTianye LiMYMengya Yang

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Overview

Multicenter cross-sectional study found that higher SIRI levels increase AF risk in COPD, suggesting a potential predictive role.

Key Points

  • Each 1-unit increase in SIRI corresponds to a 4.6% higher risk of atrial fibrillation in chronic obstructive pulmonary disease patients.
  • 19.85% of the study population, consisting of hospitalized COPD patients, had atrial fibrillation.
  • A significant linear dose–response relationship between systemic inflammation response index and atrial fibrillation risk was observed.
  • Elevated levels of SIRI may serve as a useful biomarker for assessing the risk of atrial fibrillation in COPD patients.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68c188499b7b07f3a0611c91https://doi.org/10.3389/fmed.2025.1666658
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