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September 10, 2025Russian Journal of Occupational Health and Industrial Ecology

Features of the immune and genetic status of chemical industry workers with pathology of the cardiovascular system

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Authors

НЗН.В. ЗайцеваFederal Scientific Center for Medical and Preventive Health Risk Management TechnologiesYCYulia A. ChelakovaFederal Scientific Center for Medical and Preventive Health Risk Management TechnologiesОDОleg V. DolgikhPerm National Research Polytechnic University

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Implication

Observational analysis reveals altered immune markers and genetic variants linked to cardiovascular diseases in workers, suggesting health risks from chemical exposure.

Key Points

  • Altered levels of IgG specific to N-nitrosodimethylamine are present in workers with cardiovascular diseases.
  • Workers showed a 10% higher frequency of the G allele in the endothelial NO-synthase gene associated with cardiovascular risk.
  • Elevated expression of Notch 1 receptor suggests compromised vascular health among chemical industry workers.
  • Significant differences in immune and genetic markers highlight potential risks related to chemical exposure in these workers.

Cite This Study

Зайцева et al. (2025) studied this question.

synapsesocial.com/papers/68c189e79b7b07f3a0613d9dhttps://doi.org/10.31089/1026-9428-2025-65-7-433-439
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