Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 1, 2026Journal of the Egyptian Public Health AssociationOpen Access

Integrated evaluation of environmental monitoring, rheumatoid arthritis biomarkers, and genetic variants in textile dyeing workers

View Full Paper
Ask AI
Bookmark
Share

Authors

ASAmal Saad-HusseinESEman M. ShahyMTMona M. Taha

Discussion

Loading...

Member takes

Overview

Cross-sectional study evaluates environmental factors and genetic risks for rheumatoid arthritis in textile workers, suggesting health interventions.

Key Points

  • To assess gene-environment interactions as a potential risk factor for rheumatoid arthritis in textile dyeing workers.
  • Cross-sectional comparative study including 140 exposed male workers and 130 matched controls.
  • Air monitoring of pollutants conducted over 12 months.
  • Estimation of rheumatoid arthritis biomarkers and genetic polymorphisms in both groups.
  • Significantly higher levels of anti-CCP, CRP, RF, and ANA in exposed workers compared to controls.
  • Environmental pollutants differed between sections, with higher concentrations in the dyeing area.
  • Multivariate analysis indicated a significant interaction between CYP2E1, GST polymorphisms, and environmental exposures on RF levels.

Cite This Study

Saad-Hussein et al. (2026) studied this question.

synapsesocial.com/papers/6a44ae015cd2549c8bc435b1https://doi.org/10.1186/s42506-026-00217-2
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Oxidative–antioxidant endogenous role on hepatic problems in textile-dyeing workers2024 · 1 citations
  2. 2Integrated evaluation of workplace exposures and biomarkers of bladder cancer among textile dyeing workers2024 · 2 citations
  3. 3Features of the polymorphism of the ADRB2 Arg16Gly and HTR2A (rs7997012) genes in workers at the sylvinite concentrating factory2024
  4. 4Features of the immune and genetic status of chemical industry workers with pathology of the cardiovascular system2025
  5. 5Airborne Pollutants and Their Relation to Pulmonary Impairment and X-Ray Repair Cross-Complementing 1 Gene Variants in Aluminum Smelter Workers2026