Endocrine Mucin-Producing Sweat Gland Carcinoma of the Eyelid: A Comprehensive Review of a Rare Entity

Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid is a rare, low-grade adnexal neoplasm with neuroendocrine differentiation, primarily affecting the periocular skin of elderly individuals [1,2]. This review provides an in-depth analysis of the histopathological features, immunohistochemical profile, clinical presentation, and differential diagnosis of EMPSGC, with a comparative perspective against solid papillary carcinoma (SPC) of the breast. The aim is to equip pathologists with the knowledge necessary for accurate diagnosis and to highlight the importance of recognizing this entity in the context of other eyelid and breast lesions.