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Assessment and treatment of frail patientns living with multiple myeloma. A guideline on behalf of the UK Myeloma Research Alliance Frailty Group

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Frail patients with multiple myeloma experience worse clinical outcomes and higher treatment discontinuation rates.
The guideline emphasizes the need for assessing frailty to tailor treatments that optimize healthspan and quality of life.
Validated tools for identifying frail patients include the International Myeloma Working Group Frailty Score and the Clinical Frailty Score.
The aim is to balance effective treatment with reduced toxicity to enhance overall survival in frail populations.

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Guideline outlines treatment recommendations for frail patients with multiple myeloma, suggesting doses to minimize toxicity.

Moore et al. (2025) studied this question.

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