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September 10, 2025International Journal of Environmental Research and Public HealthOpen Access

Predictors of Major Amputation and Mortality in Infected Diabetic Foot Ulcers: A Retrospective Nationwide Inpatient Sample Study

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Authors

LZLior Ben ZviTechnion – Israel Institute of Technology DMDavid MamanTechnion – Israel Institute of Technology MMMichael MargulisCarmel Medical Center

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Implication

Retrospective study identifies key predictors of major amputation and mortality in infected diabetic foot ulcers, highlighting the role of comorbidities.

Key Points

Major amputation is associated with the highest in-hospital mortality rate at 1.00%, indicating severe risks for patients.
Comorbidities like sepsis and hypertension significantly impact amputation and mortality rates, necessitating targeted management.
Statistical analyses reveal shifts in treatment patterns for diabetic foot ulcers from 2016 to 2019, with trends toward minor amputations.
Logistic regression identifies sepsis and myocardial infarction as key predictors of major amputation and mortality, stressing early intervention.

Cite This Study

Zvi et al. (2025) studied this question.

synapsesocial.com/papers/68c1924e9b7b07f3a0616b4e https://doi.org/10.3390/ijerph22091387

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Implication

Retrospective study identifies key predictors of major amputation and mortality in infected diabetic foot ulcers, highlighting the role of comorbidities.

Predictors of Major Amputation and Mortality in Infected Diabetic Foot Ulcers: A Retrospective Nationwide Inpatient Sample Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Predictors of Major Amputation and Mortality in Infected Diabetic Foot Ulcers: A Retrospective Nationwide Inpatient Sample Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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