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September 5, 2025

Supplementary Data from GALNT7 Stratifies dMMR/MSI Colorectal Cancer into Distinct Molecular Subsets Associated with Prognosis and PD-L1 Expression

Hiroya Suzuki Hirokazu Okayama Shotaro Nakajima Katsuharu Saito Ryo Kanoda Yuya Maruyama Akira Matsuishi Takuro Matsumoto Misato Ito Shun Chida Wataru Sakamoto Motonobu Saito Zenichiro Saze Tomoyuki Momma Kosaku Mimura Koji Kono

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Key Points

Distinct molecular subsets identified through GALNT7 stratification may influence prognosis.
Prognostic differences linked to GALNT7 with significant associations to PD-L1 expression.
Molecular subset analysis in dMMR/MSI colorectal cancer highlights key therapeutic targets.
Findings could guide personalized treatment approaches based on molecular characterization.

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Implication

Assessment of GALNT7 identifies distinct molecular subsets in colorectal cancer, suggesting differences in PD-L1 expression.

Abstract

Supplementary Table S1-S7, Suuplemntary Figure S1-S16

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Cite This Study

Suzuki et al. (2025) studied this question.

synapsesocial.com/papers/68c192579b7b07f3a0616e58 https://doi.org/10.1158/2767-9764.30060741

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure 4 from GALNT7 Stratifies dMMR/MSI Colorectal Cancer into Distinct Molecular Subsets Associated with Prognosis and PD-L1 Expression2025
2Figure 1 from GALNT7 Stratifies dMMR/MSI Colorectal Cancer into Distinct Molecular Subsets Associated with Prognosis and PD-L1 Expression2025
3Data from GALNT7 Stratifies dMMR/MSI Colorectal Cancer into Distinct Molecular Subsets Associated with Prognosis and PD-L1 Expression2025
4Figure 2 from GALNT7 Stratifies dMMR/MSI Colorectal Cancer into Distinct Molecular Subsets Associated with Prognosis and PD-L1 Expression2025
5Supplementary Figure 1 from Genomic Characterization and Clinical Outcomes of Patients with Peritoneal Metastases from the AACR GENIE Biopharma Collaborative Colorectal Cancer Registry2024