Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025PathogensOpen Access

Differential Gene Expression and Protein–Protein Interaction Networks in Bovine Leukemia Virus Infected Cattle: An RNA-Seq Study

View Full Paper
Ask AI
Bookmark
Share

Authors

AMAna Silvia González MéndezMinistry of Agriculture and ForestryMAMohammad Mehdi AkbarinIslamic Azad University, MashhadFCFernando Cerón-TéllezMinistry of Agriculture and Forestry

Discussion

Loading...

Member takes

Overview

RNA-seq analysis reveals differential gene expression and immune responses in cattle, suggesting pathways to lymphoma development.

Key Points

  • The analysis found that transcription activation factors were upregulated in asymptomatic carriers of bovine leukemia virus compared to healthy controls.
  • Compared to healthy controls, anti-inflammatory cytokines increased in cattle with persistent lymphocytosis, indicating altered immune responses.
  • RNA-seq was employed to analyze gene expression and protein–protein interaction networks across different cattle groups affected by bovine leukemia virus.
  • The findings suggest that certain protein interactions may play a critical role in the oncogenesis process related to severe BLV infections.

Cite This Study

Méndez et al. (2025) studied this question.

synapsesocial.com/papers/68c192579b7b07f3a0616f24https://doi.org/10.3390/pathogens14090887
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses2024 · 15 citations
  2. 2Advances in Analyzing Virus-Induced Alterations of Host Cell Splicing2018 · 68 citations
  3. 3The nuclear speckles protein SRRM2 is a new therapeutic target molecule on the surface of cancer cells2024 · 1 citations
  4. 4Virus-induced host genomic remodeling dysregulates gene expression, triggering tumorigenesis2024 · 22 citations
  5. 5The Involvement of Ubiquitination and SUMOylation in Retroviruses Infection and Latency2023 · 7 citations