The impact of the oral microbiome on women’s reproductive health

In this review, based on the analysis of specialized domestic and foreign literature allocated in the electronic libraries eLibrary and CyberLeninka, the database of medical and biological publications PubMed, a theoretical justification is presented for the problem of women’s reproductive health associated with species-specific transformation of the oral microbiome and changes in its taxonomic profile. Data on previously studied predictors affecting women’s reproductive function do not raise discussions. However, the role of the oral microbiome in the pathogenesis of reproductive dysfunction has not been fully studied. It is known that the oral microbiome consists of more than 700 species of bacteria, and its diversity can change under the influence of various factors, such as age, hormonal changes, diet and general health. These changes can have a significant impact on the overall physical condition of a woman and her somatic health. It has been proven that during pregnancy, an increase in the number of viable microorganisms is observed, which can have both positive and negative effects on the health of the mother and fetus. At the same time, imbalances in the oral microbiome can increase the risk of developing various dental diseases (gingivitis, periodontitis), as well as systemic diseases, which in turn can have a negative impact on reproductive health. Therefore, further study of the relationship between the oral microbiome and women’s reproductive function opens up new opportunities for its implementation and prediction of outcomes.