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September 10, 2025Journal of Drugs in Dermatology

Eyelid Position and Patient-Reported Aesthetic Outcomes Following Administration of Topical Oxymetazoline: A Prospective Cohort Investigation

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Authors

AKAlisha KambojUniversity of MinnesotaMHMohamed HelmyChildren Cancer HospitalBZBrian D. ZelicksonNaval Medical Center San Diego

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Implication

Prospective cohort investigation reveals significant enhancements in eyelid position and patient-reported outcomes following topical oxymetazoline administration.

Key Points

  • Topical oxymetazoline significantly improved eyelid position and aesthetic outcomes at 15 minutes post-administration.
  • Participants showed a mean increase of 0.8 mm in both margin reflex distance-1 and palpebral fissure height after treatment.
  • 85% of participants reported 51% or higher outcome satisfaction, indicating strong acceptance of the treatment.
  • No treatment-associated adverse events were reported, confirming safety during the investigation.

Cite This Study

Kamboj et al. (2025) studied this question.

synapsesocial.com/papers/68c193fb9b7b07f3a06185edhttps://doi.org/10.36849/jdd.9061
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