Clinical case highlights thrombosis as a rare cause of ischemic stroke, suggesting importance of echocardiography.
Introduction. The prevalence of sinus of Valsalva aneurysm (SOVA) in the general population is up to 0.09%, and among all congenital heart defects from 0.1 to 3.5%. One of the complications of this pathology is the development of cerebral embolism. Aim. To present a clinical case of ischemic stroke in a young patient with a rare cardiac pathology. Material and methods. The article presents a description of a clinical case of the development of ischemic stroke due to cerebral embolism from a thrombosed SOVA. A review of all published cases on the clinical significance of SOVA thrombosis in the development of stroke was conducted, and the PubMed database of medical and biological publications was analyzed. Results. A 19-years old patient without chronic diseases or bad habits was hospitalized at the vascular center for thrombectomy from the right middle cerebral artery. After successful reperfusion therapy, a diagnostic search was initiated. Transthoracic echocardiography revealed thrombosis of SOVA. During anticoagulant therapy, control transesophageal echocardiography demonstrated thrombus lysis. The patient underwent delayed resection of the SOVA. Conclusion. The study of the problem of embolic complications against the background of SOVA is low due to the extremely rare prevalence of this anomaly. Echocardiography is a key method for primary visualization of SOVA and its dynamic monitoring. There are no regulated tactics for managing patients with SOVA thrombosis.
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Mekhriakov et al. (2025) studied this question.
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