Assessment of Cardiovascular Dysfunction in Cirrhosis of Liver in Reference to Child-Pugh Score: A Cross-Sectional Observational Study

Background: Cirrhosis of the liver is associated with significant hemodynamic and structural cardiovascular changes including reduced systemic vascular resistance, increased arterial compliance, and latent or overt cardiac dysfunction. Diastolic dysfunction, in particular, is an independent predictor of mortality in cirrhosis. Despite this, cardiovascular evaluation in cirrhosis remains under-investigated. To assess Objective: cardiovascular dysfunction in cirrhosis of liver in correlation with Child-Pugh Score. This observat Methods: ional cross-sectional study included 50 adult cirrhotic patients. Clinical, biochemical, and radiological criteria were used to confirm cirrhosis. Cardiac evaluation was performed using ECG and 2D echocardiography. The severity of cirrhosis was stratified using the Child-Pugh classification. Statistical analysis included percentages and proportions. Majority of patients were male (82%), aged 31–60 years (66%). The pred Results: ominant etiology was alcohol (70%). Diastolic dysfunction was observed in 35% (Child B) and 40.7% (Child C) patients. QTc prolongation and RV strain pattern increased with severity. Moderate-to-severe systolic dysfunction and pulmonary hypertension were only seen in Child C group. Cardiovascular Conclusion: dysfunction, including diastolic and systolic dysfunction, QTc prolongation, and pulmonary hypertension, progressively correlate with worsening liver disease severity as per Child-Pugh classification. Early cardiovascular evaluation should be emphasized in advanced cirrhosis to improve prognosis.