Study of Cardiac Profile in Patients of Liver Cirrhosis

Background: Liver cirrhosis is the production, in response to chronic liver injury, of degenerative nodules surrounded by brous band. Cirrhotic patients may also have renal, respiratory, hemodynamic and cardiac dysfunction, which increases morbidity and mortality in addition to liver damage. The prevalence of cirrhotic cardiomyopathy is estimated to be between 40 - 50 % in cirrhosis. Present study was aimed to study cardiac prole in patients of liver cirrhosis. Material and Methods: Present study was single-center, observational, cross-sectional study, conducted in patients of age > 18 years, diagnosed case of liver cirrhosis. Child-Pugh-Turcotte Score & MELD Score were calculated. Results: Present study included a total of 103 study participants. The mean age of the study participants was 46.66 ± 9.31 years, majority were males (90.29%) History of alcohol (85.44%) was the most common etiology seen followed by Hepatitis B (9.71%). According to their Child Pugh scores, most (88.35%) of the patients of liver cirrhosis belonged to class C, According to their MELD scores most (88.35%) of the patients of liver cirrhosis belonged to class 3. We found a statistically signicant association between the Child Pugh's class and MELD class (χ2 (1, n=103) =52.956, p = 0.001). The patients of liver cirrhosis who participated in our study are disproportionately distributed in CPclass C and MELD class 3 as compared to the CPclass B and MELD class 2. Conclusion: Diastolic dysfunction is common in patients of liver cirrhosis irrespective of CPand MELD class. Patients of CPclass C and MELD class 3 should be monitored for QTprolongation.