Clinical trial shows significant hair growth in men with androgenetic alopecia, indicating safety with few side effects.
Background: Androgenetic alopecia is a progressive, patterned hair loss in genetically predisposed individuals due to exaggerated response to androgens, affecting both males and females. Aim And Objective: This study evaluates the effectiveness and safety of oral minoxidil in male pattern hair loss, using clinical and photographic assessments, while monitoring for side effects. Material And Methodhology: 100 males with androgenetic alopecia (Grade III–V) received 5 mg oral minoxidil daily for 24 weeks. Efficacy and side effects were assessed using clinical, photographic, and self-assessment methods. Results: The study showed significant hair growth, with a 20.3% increase in hair density by 28 weeks. Side effects included hypertrichosis (12%), oedema, hypotension, and minor skin reactions. Conclusion: Oral minoxidil 5 mg daily effectively promotes hair growth in men with AGA. It's affordable and generally safe, though caution is advised in older patients or those with cardiovascular risks.
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Yadav et al. (2025) studied this question.
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