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September 10, 2025

attenuates acute lung injury by regulating the differentiation and function of myeloid-derived suppressor cells.

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Authors

LWLingyu WeiEast China University of Science and TechnologyTSTong ShuWannan Medical CollegeMWMinghui WangKunming Medical University

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Implication

Experimental analysis reveals TW reduces myeloid-derived suppressor cells and cytokine levels in acute lung injury models, suggesting a potential therapeutic role.

Key Points

  • TW treatment significantly improved lung injury outcomes compared to LPS exposure, reducing inflammation and injury severity.
  • Histopathological scoring showed severe lung damage in the LPS group, while TW treatment resulted in improved scores (P<0.05).
  • Cytokine levels like IL-6 and TNF-α were lower in the LPS+TW group versus the LPS group, indicating anti-inflammatory effects.
  • Flow cytometry demonstrated reduced MDSC proportions in lung tissues with TW treatment, potentially enhancing immune response.

Cite This Study

Wei et al. (2025) studied this question.

synapsesocial.com/papers/68c199e89b7b07f3a061b6a2https://doi.org/10.11817/j.issn.1672-7347.2025.240424
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Also Consider

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