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September 10, 2025

Evaluation of Analgesic, and CNS Depressant Activities of Ethanolic Extract of Roots of Heritiera fomes Buch.- Ham.

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Authors

FRFarhana Alam RipaABAdwiza Chakraborty BishakhaSTSusmita Deb Tonni

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Overview

The study evaluates analgesic and CNS depressant properties in Swiss albino mice, suggesting strong effects from the ethanolic extract.

Key Points

  • The ethanolic extract of Heritiera fomes exhibits significant analgesic effects, reducing pain responses in a dose-dependent manner.
  • In the study, a maximum of 68.08% inhibition of the writhing reflex was observed at 300 mg/kg, compared to 76.45% for Diclofenac-Na.
  • CNS depressant activities were measured using thiopental sodium-induced sleeping time, showing prolonged sleep duration in treated mice.
  • The findings indicate that further research is necessary to understand the precise mechanisms of action and conduct phytochemical analysis.

Cite This Study

Ripa et al. (2024) studied this question.

synapsesocial.com/papers/68c199f49b7b07f3a061be38https://doi.org/10.62624/jbep00.0020
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