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September 10, 2025Regional Anesthesia The Journal of Neural Blockade in Obstetrics Surgery & Pain Control

Unexplained Neurologic Deficit After Uneventful Combined Spinal and Epidural Anesthesia for Cesarean Delivery

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Authors

MPM. J. PaechScience Oxford

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Implication

This case highlights an unexplained neurologic deficit after spinal and epidural anesthesia, suggesting potential neurotoxic effects.

Key Points

  • A patient experienced buttock numbness following spinal and epidural anesthesia during cesarean delivery.
  • Imaging revealed no major abnormalities, while recovery took 7 months, indicating possible neurotoxicity from medications.
  • Local anesthetic neurotoxicity is considered a plausible cause, despite a good safety record for bupivacaine.
  • The case underscores the need for awareness of neurologic risks associated with spinal and epidural anesthesia.

Cite This Study

M. J. Paech (1997) studied this question.

synapsesocial.com/papers/68c19ab49b7b07f3a061c997https://doi.org/10.1136/rapm-00115550-199722050-00015
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Parturients Vulnerability to Hyperbaric Bupivacaine-Induced Neurotoxicity After Intrathecal Administration: A Series of Four Cases2026 · 1 citations
  2. 2Is Spinal Analgesia or Anesthesia Safe After Labor Epidural Analgesia? Reporting Two Cases of High Neuraxial Block and Mini-Review of the Literature2025
  3. 3Low Dose of Intrathecal Hyperbaric Bupivacaine Combined with Epidural Lidocaine for Cesarean Section ??? A Balance Block Technique1994 · 77 citations
  4. 4Spinal Anesthesia for Elective Cesarean Section: Bupivacaine Associatedwith Different Doses of Fentanyl – A Retrospective Study2025
  5. 5Combined Spinal-Epidural Anesthesia for Cesarean Delivery: Dose-Dependent Effects of Hyperbaric Bupivacaine on Maternal Hemodynamics2006 · 85 citations