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September 10, 2025Frontiers in NutritionOpen Access

The role of body composition, cardiometabolic parameters, and resting substrate oxidation in protecting against metabolic syndrome in adolescents with obesity

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Authors

MDMattia D’AllevaSLStefano LazzerMMMaria De Martino

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Overview

Explores links between body composition and cardiometabolic parameters in adolescents with obesity, suggesting new intervention strategies.

Key Points

  • Metabolic syndrome was found in 27% of adolescents with obesity, highlighting a significant public health issue.
  • Adolescents with metabolic syndrome exhibited 15 kg higher body mass and 0.02 g·min −1 greater carbohydrate oxidation at rest.
  • Analysis involved 730 adolescents using body composition tests and indirect calorimetry to assess substrate metabolism.
  • Higher fat-free mass and HDL cholesterol levels were protective against metabolic syndrome, emphasizing the role of body composition.

Cite This Study

D’Alleva et al. (2025) studied this question.

synapsesocial.com/papers/68c19f9c54b1d3bfb60db5b7https://doi.org/10.3389/fnut.2025.1624696
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