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September 10, 2025Microbiology SpectrumOpen Access

IncN-R plasmid co-integration contributing to extensive drug resistance in Escherichia coli isolated from a canine prostatic abscess

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Authors

PSParinya SroithongkhamCLChavin LeelapsawasRIRusmin Indra

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Overview

Novel multi-replicon incn-r plasmid contributes to drug resistance in escherichia coli, indicating urgent public health implications.

Key Points

  • The incn-r plasmid pCUVET19-1426.1 drives extensive drug resistance in escherichia coli, posing clinical challenges.
  • Characterization revealed 12 antimicrobial resistance genes in the new escherichia coli sequence type 13037.
  • Genomic analysis and antimicrobial resistance profiling were conducted to explore plasmid evolution and transferability.
  • Findings suggest a critical need for genomic surveillance to monitor plasmid evolution for antimicrobial resistance.

Cite This Study

Sroithongkham et al. (2025) studied this question.

synapsesocial.com/papers/68c19fa854b1d3bfb60db871https://doi.org/10.1128/spectrum.00790-25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Complete-genome analysis reveals diverse and conserved antimicrobial resistance platforms in Enterobacterales from veterinary diagnostic cases in Saint Kitts and Nevis2026
  2. 2The IncC and IncX1 resistance plasmids present in multi-drug resistant Escherichia coli strains isolated from poultry manure in Poland2024 · 1 citations
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  4. 4A newly-identified IncY plasmid from multi-drug resistant Escherichia coli isolated from dairy cattle feces in Poland2024
  5. 5Persistent multispecies dissemination of <i>armA</i> -carrying IncR plasmids among clinical and environmental bacterial populations in a Spanish veterinary hospital2025