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September 10, 2025Addiction ResearchOpen Access

Nature Vs Nurture: Cocaine Exposed Spermatogonia Impact Behavior and Executive Functions of Naïve Offspring

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Authors

OTOrien L. Tulp

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Overview

Observational analysis reveals dose-related behavioral changes in offspring of naïve females, suggesting epigenetic impacts of male cocaine exposure.

Key Points

  • Offspring exhibited dose-related decreases in activity, with increased effects at higher cocaine doses.
  • Behavioral assessments showed latency in exploratory activity in male offspring born to opiate-treated fathers.
  • Cocaine exposure during spermatogenesis may lead to persistent behavioral changes in offspring, predisposing them to future issues.
  • Results indicate potential long-term effects on executive functions and behavior in naïve offspring exposed to cocaine.

Cite This Study

Orien L. Tulp (2025) studied this question.

synapsesocial.com/papers/68c1a27254b1d3bfb60ddcd2https://doi.org/10.33425/2639-8451.1053
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