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September 10, 2025Deleted JournalOpen Access

The promise and pitfalls: interpreting dual β-lactam success in Mycobacterium abscessus with caution

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Observational case reports show dual β-lactam may improve outcomes in mycobacterium abscessus, highlighting the need for standardization.

Dual β-lactam therapy showed promising in vitro synergy for treating mycobacterium abscessus, but further investigation is required.
Cases report successful outcomes in two pediatric patients with mycobacterium abscessus, indicating potential benefits of this therapy.
Challenges include the lack of standardized synergy testing and limited in vivo data, calling for more rigorous clinical research.
Clinical use of dual β-lactam should be contingent on thorough appraisal of existing data, as evidence remains limited and potentially biased.

Carlos Mejía-Chew (2025) studied this question.

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September 10, 2025Deleted JournalOpen Access

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Authors

Observational case reports show dual β-lactam may improve outcomes in mycobacterium abscessus, highlighting the need for standardization.

Dual β-lactam therapy showed promising in vitro synergy for treating mycobacterium abscessus, but further investigation is required.
Cases report successful outcomes in two pediatric patients with mycobacterium abscessus, indicating potential benefits of this therapy.
Challenges include the lack of standardized synergy testing and limited in vivo data, calling for more rigorous clinical research.
Clinical use of dual β-lactam should be contingent on thorough appraisal of existing data, as evidence remains limited and potentially biased.

Carlos Mejía-Chew (2025) studied this question.

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