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Biosynthesis of guanidine-containing natural products in cyanobacteria

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Cyanobacteria produce diverse natural products, with unique guanidine modifications facilitating biological interactions.
Recent findings reveal enzymatic processes for guanidine incorporation, including N-prenylation and cyclization.
The review emphasizes the metabolic versatility of cyanobacteria, highlighting potential for therapeutic applications.
Understanding these transformations lays groundwork for future advancements in enzyme engineering and discovery.

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Review summarizes enzymatic transformations for guanidine installation in cyanobacteria, indicating novel biosynthetic strategies.

Zhang et al. (2025) studied this question.

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