Cohort study links prenatal maternal depressive symptoms to functional brain connectivity changes in adolescents, suggesting implications for neurodevelopment.
Key Points
Prenatal maternal depressive symptoms are linked to increased global efficiency in brain connectivity over time.
Children exposed to prenatal depressive symptoms showed significant changes in functional brain connectivity metrics.
Assessments included resting-state functional magnetic resonance imaging scans from a large cohort of mother-child pairs.
Findings underscore the importance of maternal mental health during pregnancy for understanding child neurodevelopment.