Effect of low-level laser therapy on postoperative pain following root canal filling with resin-based and bioceramic sealers: A double-blinded randomized clinical trial

Context: One of the most important aspects of endodontic treatment is pain management. Studies have reported conflicting results regarding postoperative pain following obturation with different sealers. Bioceramic sealers are promising alternative to other sealers. Low-level laser therapy (LLLT) is found to reduce postoperative pain. Aim: The study aimed to evaluate postoperative pain following root canal obturation with bioactive glass (BG)-based and resin-based sealer with or without adjunctive LLLT. Materials and Methods: Forty patients were included in the study according to the inclusion and exclusion criteria. Root canal treatment was performed using NiTi rotary instruments. Patients were randomly distributed into four groups of 10 in each: Group 1, resin-based sealers without LLLT; Group 2, resin-based sealers with LLLT; Group 3 bioceramic-based sealers without LLLT; and Group 4, bioceramic-based sealers with LLLT. Postoperative pain levels on the 1 st , 3 rd , 5 th , and 7 th day were recorded on the Visual Analog Scale. One-way ANOVA and least significant difference post hoc tests were performed to analyze the data ( P < 0.05). Results: BG-based sealers in conjunction with LLLT showed the least postoperative pain compared to the resin-based sealers. Conclusion: Bioceramic-based sealers with LLLT may be used as an alternate strategy to control postoperative pain.