Case study identifies a conjunctival nevus exhibiting suspicious characteristics, suggesting malignancy.
A 47 year old female presented with a conjunctival melanocytic nevus in her right eye which was rapidly increasing in size, adherent to the underlying sclera and encroaching the cornea, arising the suspicion of malignancy. Anterior segment OCT (AS-OCT) performed revealed an intralesional cystic mass not penetrating the corneal stroma or anterior chamber angle. An excisional biopsy was planned wherein a wide surgical excision of the lesion was performed using “no-touch technique.” A double-thaw cryo together with 0.04% mitomycin C was applied over the excised margin of the conjunctiva. Amniotic membrane grafting was done over the bare area of the sclera and cornea. Histopathological examination revealed round to oval nevus cells having round to oval nuclei with abundant cytoplasm with no evidence of atypia or mitotic figures, thereby confirming the benign nature of the lesion, thus corroborating the importance of histopathological confirmation in such suspicious conjunctival lesions.
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Ojha et al. (2025) studied this question.
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