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September 10, 2025International Journal of Veterinary Medicine

Determination of the sensitizing activity of a gel with octenidine dihydrochloride

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Authors

KIK. P. IvanovaALA. M. Lunegov

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Overview

Animal study reveals no skin sensitization in octenidine dihydrochloride gel, suggesting safety for use.

Key Points

  • No skin sensitization symptoms were observed in guinea pigs tested with octenidine dihydrochloride gel.
  • Skin tests showed no redness, itching, or local temperature rise, indicating low sensitizing activity.
  • In a conjunctival test, redness occurred briefly but resolved within 24 hours, with no systemic effects noted.
  • The study adhered to established guidelines for preclinical testing of medicines, contributing to its credibility.

Cite This Study

Ivanova et al. (2025) studied this question.

synapsesocial.com/papers/68c1a78854b1d3bfb60e1360https://doi.org/10.52419/issn2072-2419.2025.2.148
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