Changes in serum amyloid A of cats and C-reactive protein of dogs in pneumonia

A full-fledged diagnosis of pneumonia should include testing for the level of acutephase inflammatory proteins. C-reactive protein is widespread in dogs, and its concentration increases as early as 6-8 hours after the onset of inflammation. Cats have serum amyloid A, whose concentration increases 24-48 hours after the onset of inflammation. Currently, the immunofluorescence method is widely used to determine acutephase inflammatory proteins. The authors compared the levels of acute-phase inflammatory proteins in healthy animals and sick animals (before and after treatment). A statistically significant difference was revealed between patients before treatment and healthy animals. A statistically significant difference was found between recovered and healthy cats. There were no statistically significant differences between recovered and healthy dogs. The level of serum amyloid A in sick cats significantly increased 8-fold relative to healthy ones (p<0.01), and upon recovery returned to the standard values, but was significantly higher by 32.6% than in healthy animals (p><0.01). The level of Creactive protein in sick dogs significantly increased by 7.6 times relative to healthy dogs (p><0.01), and upon recovery returned to the standard values and had no significant difference with healthy animals. Determining the concentration of C-reactive protein in dogs and serum amyloid A in cats before starting therapy and after antibiotic therapy helps to decide whether to extend treatment if necessary and is one of the criteria for the success of therapy. > < 0.01), and upon recovery returned to the standard values, but was significantly higher by 32.6% than in healthy animals (p < 0.01). The level of Creactive protein in sick dogs significantly increased by 7.6 times relative to healthy dogs (p < 0.01), and upon recovery returned to the standard values and had no significant difference with healthy animals. Determining the concentration of C-reactive protein in dogs and serum amyloid A in cats before starting therapy and after antibiotic therapy helps to decide whether to extend treatment if necessary and is one of the criteria for the success of therapy.