Changes in biochemical parameters of blood serum during postpartum paresis in cows

Postpartum paresis is a widespread disease of dairy cows, occurring in industrial animal husbandry and in private farms. Postpartum paresis is registered under conditions of intensive dairy farming in all countries of the world. However, despite its wide distribution, its etiology and pathogenesis remain insufficiently studied. The aim of the study was to analyze biochemical changes in the blood serum of cows with postpartum paresis. Object of the study - blood of calving cows with signs of postpartum paresis and without pathology of the postpartum period as a control. The object of the study was blood serum from the jugular vein. The material was collected in vacuum tubes 1-2 days after calving. The study was carried out in the Omsk region “Omsk regional veterinary laboratory” on an automatic biochemical analyzer BioLit-8020. Statistical processing of the study results was carried out using Statistica 13.0 program (StatSoft Inc, USA). The parametric Student's t-criterion for independent samples was used for comparison of intergroup indices. The correlation between alkaline phosphatase and calcium concentration was established using the Kendall-Tau criterion. The study revealed statistically significant changes in the content of total protein (p = 0.006), globulins (p = 0.031), calcium (p < 0.001), creatinine (p = 0.012), and alkaline phosphatase activity (p = 0.041). The relationship of the studied indicators with the violation of phosphoruscalcium metabolism is reflected. The decrease in functional activity of kidneys and liver deserves special attention, which should be taken into account in the development of therapeutic and preventive measures.