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The emergence of mRNA therapeutics: A new era in precision medicine

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This review highlights advances in mRNA therapeutics and their implications for cancer immunotherapy and gene editing.

mRNA therapeutics may revolutionize personalized medicine by offering new treatment options.
Clinical trials for over 150 mRNA-based treatments highlight significant advancements, especially in oncology.
Lipid nanoparticle-encapsulated mRNA mediums have potentially restored more than 50% of missing proteins in preclinical studies.
Challenges in mRNA therapeutics include optimizing delivery methods and minimizing immune responses.

Sakat et al. (2025) studied this question.

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