A Case of Coxsackie B Causing Multiorgan Failure

Coxsackie B typically affects one organ system at a time – heart, liver or lungs. There is sparce literature on multiorgan failure induced by the Coxsackie B virus. Here we describe a case of Coxsackie B in a young female with type 1 diabetes mellitus. At admission to the hospital, the patient was presented with complaints of fatigue, lethargy, nausea, vomiting and hypoglycemia. Additionally, the patient was found to have myopericarditis, transaminitis, and acute renal failure requiring temporary hemodialysis. While myopericarditis is frequently associated with Coxsackie B, both hepatic and/or renal failure are uncommon presentations. Treatment is largely supportive with NSAIDs as the most effective treatment for myopericarditis.