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September 10, 2025Pharmacology and Toxicology of Natural Medicines (ISSN 2756-6838)

Protective Effect of Pleurotus tuberregium Polysaccharide (PTP) and Ganoderma lucidum Polysaccharide (GLP) on Lead-Induced Testicular Derangement in Rats

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Authors

MSMichael Oluwatosin SobowaleUniversity of Ilorin OOOlufunke E. OlorundareUniversity of Ilorin SASaheed O. AfolabiUniversity of Ilorin

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Implication

Clinical trial evaluated protective effects of polysaccharides on lead-induced testicular damage, highlighting antioxidant and anti-inflammatory benefits.

Key Points

GLP and PTP treatment improved sperm motility and viability in lead-exposed rats, indicating protective effects.
Significant reductions in inflammatory markers were observed in rats treated with GLP and PTP after lead exposure.
Histological evaluation showed normal seminiferous tubules in treated groups, contrasting with lead-only group showing damage.
Administration of GLP and PTP demonstrated enhanced antioxidant levels, suggesting protection against gonadotoxicity.

Cite This Study

Sobowale et al. (2025) studied this question.

synapsesocial.com/papers/68c1aab854b1d3bfb60e2c8a https://doi.org/10.52406/ptnm.v5i3-4.118

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Implication

Clinical trial evaluated protective effects of polysaccharides on lead-induced testicular damage, highlighting antioxidant and anti-inflammatory benefits.

Protective Effect of Pleurotus tuberregium Polysaccharide (PTP) and Ganoderma lucidum Polysaccharide (GLP) on Lead-Induced Testicular Derangement in Rats

Discussion

Member takes

Implication

Key Points

Cite This Study

Protective Effect of Pleurotus tuberregium Polysaccharide (PTP) and Ganoderma lucidum Polysaccharide (GLP) on Lead-Induced Testicular Derangement in Rats

Discussion

Member takes

Implication

Key Points

Cite This Study

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