Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 1, 2024European Journal of Anatomy

Investigation of the effects of pomegranate juice against toxicity in the testes in lead-administered rats

View Full Paper
Ask AI
Bookmark
Share

Authors

HPHıdır PekmezMalatya Turgut Özal ÜniversitesiEAEbru AnnaçAdıyaman UniversityÖBÖzgür BulmuşBalıkesir University

Discussion

Loading...

Member takes

Implication

Controlled animal study demonstrates that pomegranate juice reduces testicular toxicity and restores testosterone in lead-exposed rats, highlighting its protective potential.

Key Points

  • Pomegranate juice mitigates lead acetate toxicity in rat testicular tissue by reducing lipid peroxidation and restoring depressed testosterone levels.
  • In 28 rats, malondialdehyde levels decreased while glutathione s-transferase and carboxylesterase activities improved following 1 mL pomegranate juice intake.
  • Controlled assessment across four experimental groups confirms that testicular glutathione depletion is reversed—rat model; further preclinical validation is needed.

Cite This Study

Pekmez et al. (2024) studied this question.

synapsesocial.com/papers/68e59f9eb6db643587539adfhttps://doi.org/10.52083/zelq3438
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Protective Effect of Pleurotus tuberregium Polysaccharide (PTP) and Ganoderma lucidum Polysaccharide (GLP) on Lead-Induced Testicular Derangement in Rats2025
  2. 2Annona squamosa Fruit Extract Ameliorates Lead Acetate-Induced Testicular Injury by Modulating JAK-1/STAT-3/SOCS-1 Signaling in Male Rats2024 · 15 citations
  3. 3Ascorbic acid attenuates lead-induced oxidative stress and testosterone suppression in male Wistar rats2026
  4. 4Protective effect of pomegranate seed oil against lead acetate-induced toxicity on the hippocampus and bone marrow in rats.2026
  5. 5Targeting JAK2/STAT3, NLRP3/Caspase-1, and PK2/PKR2 Pathways with Arbutin Ameliorates Lead Acetate-Induced Testicular Injury in Rats2024 · 24 citations