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April 23, 20260 citations

Protective effect of pomegranate seed oil against lead acetate-induced toxicity on the hippocampus and bone marrow in rats.

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MAMohaddeseh Sadat AlaviMashhad University of Medical SciencesAHAzar HosseiniMashhad University of Medical SciencesFTFereshte TorabiMashhad University of Medical Sciences

Key Points

  • The aim is to evaluate if pomegranate seed oil can protect against lead-induced damage in the hippocampus and bone marrow.
  • Administered lead acetate to rats to induce toxicity.
  • Treated with pomegranate seed oil to assess protective effects.
  • Evaluated damage in bone, bone marrow, and hippocampus.
  • Pomegranate seed oil significantly reduced oxidative stress.
  • Lead-induced damage in bone and hippocampus was mitigated.
  • Improvement observed in overall tissue health.

Abstract

PSO could protect against lead-induced damage in bone, bone marrow, and hippocampus of treated animals through reduction of oxidative stress.

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Cite This Study

Alavi et al. (2026) studied this question.

synapsesocial.com/papers/69e9b85585696592c86eba17https://doi.org/10.22038/ajp.2025.26495
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Borage Seed Oil Against Lead Acetate Neurotoxicity in Rats2026
  2. 2Investigation of the effects of pomegranate juice against toxicity in the testes in lead-administered rats2024
  3. 3Protective effect of pomegranate seed oil against H2O2 -induced oxidative stress in cardiomyocytes.2017 · 16 citations
  4. 4Pomegranate seed oil attenuates palmitic acid‐induced hepatic injury through modulation of oxidative stress: insights from GC ‐Q‐ TOF ‐ MS ‐based metabolomics2026
  5. 5Preventive effects of pomegranate seed oil on transient middle cerebral artery occlusion via the Keap1/Nrf2/NQO1 pathway in the rats cortex2026